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Thyronamine

Thyronamine is a type of decarboxylated and deiodinated metabolite of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3). The word thyronamine can refer to either the family of molecules, or the specific molecule from which they are derived.

Types

The group includes:

Thyronamine (T0AM)
3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), an intracellular G protein-coupled receptor
3,5-Diiodothyronamine (T2AM)
3,5,3'-Triiodothyronamine (T3AM)

References

(2011). "Thyronamines - Past, Present, and Future". Endocrine Reviews.

Info: Wikipedia Source

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biogenic-amines methoxyphenethylamines 4-hydroxyphenyl-compounds thyroid taar1-agonists aminoethyl-compounds

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