2C-F

Use effects

In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists the dose of 2C-F as greater than 250mg orally and its duration as unknown. At a dose of 250mg, 2C-F produces slight and uncertain effects including possible modest closed-eye visuals and pleasant lethargy.

Interactions

Pharmacology

Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-F.

Chemistry

Properties

2C-F may be found as a brownish freebase oil, or as a white crystalline hydrochloride salt.

Synthesis

The chemical synthesis of 2C-F has been described.

Analogues

Analogues of 2C-F include 2C-B, 2C-I, 2C-C, DOF, and 25F-NBOMe, among others.

History

2C-F was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).

Society and culture

Legal status

Canada

As of October 31, 2016, 2C-F is a controlled substance (Schedule III) in Canada.

United States

2C-F is not an explicitly controlled substance in the United States. However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.

References

References

1. {{CitePiHKAL [https://www.erowid.org/library/books_online/pihkal/pihkal026.shtml 2C-F Entry in ''PiHKAL'']
2. (2011). "[[The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds]]". [[Transform Press]].
3. (2022). "Structure-activity Relation of Halogenated 2,5-Dimethoxyamphetamines Compared to their α‑Desmethyl (2C) Analogues". The FASEB Journal.
4. (4 May 2016). "Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". Government of Canada.
5. (January 2026). "Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026)". U.S. [[Department of Justice]]: [[Drug Enforcement Administration]] (DEA): Diversion Control Division.