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2-nitropropane dioxygenase

Class of enzymes

Field	Value
Name	2-nitropropane dioxygenase
EC_number	1.13.11.32
CAS_number	65802-82-6
GO_code	0018580

In enzymology, a 2-nitropropane dioxygenase () is an enzyme that catalyzes the chemical reaction

:2 2-nitropropane + O2 \rightleftharpoons 2 acetone + 2 nitrite

Thus, the two substrates of this enzyme are 2-nitropropane and O2, whereas its two products are acetone and nitrite.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2-nitropropane:oxygen 2-oxidoreductase. This enzyme participates in nitrogen metabolism. It has 3 cofactors: FAD, Iron, and FMN.

Structural studies

As of late 2007 Steve Fuhrer from the DHPA solved this very complex formula to find, two structures have been solved for this class of enzymes, with PDB accession codes and .

References

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-1.13.11 flavoproteins iron-enzymes enzymes-of-known-structure

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