Macroketone

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title: "Macroketone" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["ketones", "macrocycles"] topic_path: "general/ketones" source: "https://en.wikipedia.org/wiki/Macroketone" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::figure[src="https://upload.wikimedia.org/wikipedia/commons/6/67/Macroketone.png" caption="Chemical structure of (4''E'',6''S'',7''S'',8''S'',9''E'')-7-hydroxy-8-methoxy-4,6-dimethylcyclotetradeca-4,9-dien-1-one, a macroketone used in the synthesis of [[migrastatin]] analogs"] ::

Macroketones are macrocyclic compounds that contain a ketone functional group. Macroketones form the central rings systems of some synthetic polyketide antibiotics.;

References

References

  1. (2008). "Synthesis of Novel Macrolactam and Macroketone Analogues of Migrastatin from D-Glucal and Comparison with Macrolactone and Acyclic Analogues: A Dorrigocin A Congener Is a Potent Inhibitor of Gastric Cancer Cell Migration". European Journal of Organic Chemistry.

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ketonesmacrocycles