Cyclohexylacetone

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title: "Cyclohexylacetone" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["ketones"] topic_path: "general/ketones" source: "https://en.wikipedia.org/wiki/Cyclohexylacetone" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

| Watchedfields = |verifiedrevid = |ImageFile = Cyclohexylacetone 2D.svg|ImageSize = 190px|ImageName = |ImageFile1 = |ImageSize1 = |ImageName1 = |PIN = 1-Cyclohexylpropan-2-one |Section1={{Chembox Identifiers | ChemSpiderID_Ref = | ChemSpiderID = 60261 | UNII_Ref = | UNII = V54Y1GAG9I | PubChem = 66899 | EC_number = 203-143-9 | InChI = | InChIKey = | ChEMBL_Ref = | ChEMBL = | StdInChI_Ref = | StdInChI = 1S/C9H16O/c1-8(10)7-9-5-3-2-4-6-9/h9H,2-7H2,1H3 | StdInChIKey_Ref = | StdInChIKey = UHBZEAPZATVYKV-UHFFFAOYSA-N | CASNo_Ref = | CASNo = 103-78-6 | ChEBI_Ref = | ChEBI = | SMILES = O=C(CC1CCCCC1)C |Section2={{Chembox Properties | C = 9 | H = 16 | O = 1 | Density = 0.905 g/cm3 | pKa = | MeltingPt = | BoilingPtC = 198 to 200 | BoilingPt_notes = | Solubility =

Cyclohexylacetone (acetonylcyclohexane) is an organic compound. Cyclohexylacetone is closely related to phenylacetone being phenylacetone with the benzene ring replaced with a cyclohexane ring.

Applications

Propylhexedrine can be synthesized from cyclohexylacetone through the reductive amination of an intermediary imine over an aluminum-mercury amalgam in the presence of a hydrogen source.

: [[File:Propylhexedrine_synthesis_from_cyclohexylacetone.svg|class=skin-invert-image|450x450px]]

Another cyclohexylacetone use is in the production of droprenilamine.

References

References

  1. Merck Index 7761 - Kleeman & Engel p.774 OCDS Vol.1 p.37 (1977) I.N. p.817

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ketones