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XCL2

Protein-coding gene in the species Homo sapiens

Protein-coding gene in the species Homo sapiens

Chemokine (C motif) ligand 2 (XCL2) is a small cytokine belonging to the XC chemokine family that is highly related to another chemokine called XCL1. It is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated cells. XCL2 induces chemotaxis of cells expressing the chemokine receptor XCR1. Its gene is located on chromosome 1 in humans.

References

References

  1. (1995). "Molecular cloning and functional characterization of human lymphotactin". J Immunol.
  2. (1998). "Identification of single C motif-1/lymphotactin receptor XCR1". J Biol Chem.
  3. (1996). "Structure and expression of two highly related genes encoding SCM-1/human lymphotactin". FEBS Lett.
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cytokines
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