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WAY-208466

Chemical compound

| elimination_half-life =

1207064-61-6 (2 HCl)

WAY-208466 is a potent and highly selective full agonist of the 5-HT6 receptor. It increases GABA levels in the cerebral cortex and tolerance does not appear to occur to this action upon chronic administration. Animal studies have shown that WAY-208466 produces antidepressant and anxiolytic effects in rodents and it may also be useful in the treatment of obsessive-compulsive disorder.

References

(May 2008). "Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466". Neuropsychopharmacology.
(March 2010). "Antidepressant and anxiolytic effects of selective 5-HT(6) receptor agonists in rats". Psychopharmacology.

Info: Wikipedia Source

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5-ht6-agonists experimental-antidepressants 3-fluorophenyl-compounds tertiary-amines sulfuryl-compounds pyrrolopyridines

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