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Very-long-chain acyl-CoA dehydrogenase
| Field | Value |
|---|---|
| Name | Very-long-chain acyl-CoA dehydrogenase |
| EC_number | 1.3.8.9 |
| image | 2uxw.jpg |
| width | 270 |
| caption | Very long chain acyl-CoA dehydrogenase dimer, Human |
Very-long-chain acyl-CoA dehydrogenase (, ACADVL (gene).) is an enzyme with systematic name very-long-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase. This enzyme catalyses the following chemical reaction
: a very-long-chain acyl-CoA + electron-transfer flavoprotein \rightleftharpoons a very-long-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein
This enzyme contains FAD as prosthetic group.
References
References
- (January 1992). "Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. I. Purification and properties of very-long-chain acyl-coenzyme A dehydrogenase". The Journal of Biological Chemistry.
- (June 1995). "Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients". The Journal of Clinical Investigation.
- (April 2008). "Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase". The Journal of Biological Chemistry.
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