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TRNA-dihydrouridine20a/20b synthase (NAD(P)+)

Class of enzymes


Class of enzymes

FieldValue
NameTRNA-dihydrouridine20a/20b synthase (NAD(P)+)
EC_number1.3.1.90

TRNA-dihydrouridine20a/20b synthase (NAD(P)+) (, Dus4p) is an enzyme with systematic name tRNA-5,6-dihydrouracil20a/20b:NAD(P)+ oxidoreductase. This enzyme catalyses the following chemical reaction

: (1) 5,6-dihydrouracil20a in tRNA + NAD(P)+ \rightleftharpoons uracil20a in tRNA + NAD(P)H + H+ : (2) 5,6-dihydrouracil20b in tRNA + NAD(P)+ \rightleftharpoons uracil20b in tRNA + NAD(P)H + H+

A flavoenzyme. The enzyme specifically modifies uracil20a and uracil20b in tRNA.

References

References

  1. (April 2004). "The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs". The Journal of Biological Chemistry.
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