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TRNA-dihydrouridine16/17 synthase (NAD(P)+)
Class of enzymes
Class of enzymes
| Field | Value |
|---|---|
| Name | TRNA-dihydrouridine16/17 synthase (NAD(P)+) |
| EC_number | 1.3.1.88 |
TRNA-dihydrouridine16/17 synthase (NAD(P)+) (, Dus1p, tRNA-dihydrouridine synthase 1) is an enzyme with systematic name tRNA-5,6-dihydrouracil16/17:NAD(P)+ oxidoreductase. This enzyme catalyses the following chemical reaction
: (1) 5,6-dihydrouracil16 in tRNA + NAD(P)+ \rightleftharpoons uracil16 in tRNA + NAD(P)H + H+ : (2) 5,6-dihydrouracil17 in tRNA + NAD(P)+ \rightleftharpoons uracil17 in tRNA + NAD(P)H + H+
This enzyme specifically modifies uracil16 and uracil17 in tRNA.
References
References
- (April 2004). "The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs". The Journal of Biological Chemistry.
- (March 2002). "A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA". RNA.
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