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Tetrachlorodecaoxide

Chemical compound

Chemical compound

"Tetrachlorodecaoxide" (TCDO) is a chlorite-containing substance with claimed immunomodulatory, macrophage-activating properties. WF10 (Macrokine, Immunokine, Oxoferin) is an aqueous solution of tetrachlorodecaoxide designed for intravenous injection. Tetrachlorodecaoxide/WF10 were originally developed by Oxo Chemie. The chemical formula is given as Cl4H2O114-. This incomplete formula shows a mixture of chlorite ion, water, and molecular oxygen: "Cl4H2O114-" = 4ClO2− + H2O + O2. Oxoferin was found to be equivalent with aqueous sodium chlorite.

Tetrachlorodecaoxide / WF10 is used in the management of radiation cystitis, is effective in the treatment of diabetic foot ulcers, and is used in wound healing, where the mechanism of action is activation of the macrophage system, and increasing the partial pressure of oxygen in the wound.

References

References

  1. (June 2016). "The chlorite-based drug WF10 constantly reduces hemoglobin A1c values and improves glucose control in diabetes patients with severe foot syndrome". Journal of Clinical & Translational Endocrinology.
  2. "About Us".
  3. "Tetrachlorodecaoxide - Cl4H2O11-4". U.S. National Library of Medicine.
  4. "WF10".
  5. (Jan 1989). "Oxoferin und Natriumchlorit — Ein Vergleich". Klinische Wochenschrift.
  6. (April 2010). "Management of radiation cystitis". Nature Reviews. Urology.
  7. (March 2013). "Clinical outcomes of WF10 adjunct to standard treatment of diabetic foot ulcers". Journal of Wound Care.
  8. (September 2016). "The Efficacy and Safety of Tetrachlorodecaoxide in Comparison with Super-oxidised Solution in Wound Healing". Archives of Plastic Surgery.
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chlorites immunomodulating-drugs
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