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Table of volume of distribution for drugs
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This is a table of volume of distribution (Vd) for various medication. For comparison, those with a Vd L/kg body weight of less than 0.2 are mainly distributed in blood plasma, 0.2-0.7 mostly in the extracellular fluid and those with more than 0.7 are distributed throughout total body water.
| Medication | Vd L/kg body weight | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| heparin | author=Rang, H. P. | title=Pharmacology | publisher=Churchill Livingstone | location=Edinburgh | year=2003 | pages= | isbn=0-443-07145-4 | oclc= | doi=}} Page 103 |
| insulin | 0.05-0.1 | ||||||||
| warfarin | 0.1-0.2 | ||||||||
| sulfamethoxazole | 0.1-0.2 | ||||||||
| glibenclamide | 0.1-0.2 | ||||||||
| atenolol | 0.1-0.2 | ||||||||
| NXY-059 | 0.1-0.2 | ||||||||
| tubocurarine | 0.2-0.4 | ||||||||
| theophylline | 0.4-0.7 | ||||||||
| ethanol | 0.7-0.9 | ||||||||
| neostigmine | 0.7-0.9 | ||||||||
| phenytoin | 0.7-0.9 | ||||||||
| methotrexate | 1-2 | ||||||||
| indometacin | 1-2 | ||||||||
| paracetamol | 1-2 | ||||||||
| diazepam | 1-2 | ||||||||
| lidocaine | 1-2 | ||||||||
| glyceryl trinitrate | 2-5 | ||||||||
| morphine | 2-5 | ||||||||
| propranolol | 2-5 | ||||||||
| digoxin | 2-5 | ||||||||
| chlorpromazine | 2-5 | ||||||||
| nortriptyline | 2-5 | ||||||||
| chloroquine | 200 |
References & footnotes
References
- Rang, H. P.. (2003). "Pharmacology". Churchill Livingstone.
- Estimated with a body weight of 70 kg.
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