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Sulfur dioxygenase

Class of enzymes


Class of enzymes

FieldValue
NameSulfur dioxygenase
EC_number1.13.11.18
CAS_number37256-58-9

Sulfur dioxygenase (, sulfur oxygenase, sulfur:oxygen oxidoreductase) is an enzyme with systematic name S-sulfanylglutathione:oxygen oxidoreductase. This enzyme catalyses the following chemical reaction

: sulfur + O2 + H2O \rightleftharpoons sulfite + 2 H+ (overall reaction) : (1a) glutathione + sulfur \rightleftharpoons S-sulfanylglutathione (spontaneous reaction) : (1b) S-sulfanylglutathione + O2 + H2O \rightleftharpoons glutathione + sulfite + 2 H+

This enzyme contains iron.

In humans, sulfur dioxygenase is needed to detoxify sulfide.

References

References

  1. (July 1966). "The initial product and properties of the sulfur-oxidizing enzyme of thiobacilli". Biochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation.
  2. (July 2003). "The sulfane sulfur of persulfides is the actual substrate of the sulfur-oxidizing enzymes from Acidithiobacillus and Acidiphilium spp". Microbiology.
  3. (August 2010). "Combined treatment with oral metronidazole and N-acetylcysteine is effective in ethylmalonic encephalopathy". Nature Medicine.
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