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Sulforhodamine 101
Red fluorescent dye
Red fluorescent dye
Sulforhodamine 101 (SR101) is a red fluorescent dye. In neurophysiological experiments which comprise calcium imaging methods, it can be used for a counterstaining of astrocytes to be able to analyze data from neurons separately.{{cite journal | display-authors = 4 | author = Kang, J. | author2 = Kang N. | author3 = Yu, Y. | author4 = Zhang, J. | author5 = Petersen, N. | author6 = Tian G.-F. | author7 = Nedergaard, M. | title = Sulforhodamine 101 induces long-term potentiation of intrinsic excitability and synaptic efficacy in hippocampal CA1 pyramidal neurons |journal = Neuroscience | date = 2010 | volume = 169 | issue = 4 | pages = 1601–1609 | pmid = 20600669 | doi = 10.1016/j.neuroscience.2010.06.020 | pmc = 2918738 }}
A sulfonyl chloride derivative of sulforhodamine 101, known as Texas Red, is used for conjugation to a number of functional groups, especially primary amines.
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