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Stearidonic acid

Stearidonic acid (SDA: C18H28O2; 18:4, n-3) is an ω-3 fatty acid, sometimes called moroctic acid.

Biosynthesis

It is biosynthesized from alpha-linolenic acid (ALA: C18H30O2; 18:3, n-3) by the enzyme delta-6-desaturase, which removes two hydrogen (H) atoms.

Stearidonic acid is a precursor to eicosapentaenoic acid.

As it is a precursor to other fatty acids, there has been efforts to enhance the content off stearidonic acid in various crops, such as soybeans.

SDA is also a precursor to N-acylethanolamine (NAEs). Natural sources of this fatty acid are the seed oils of hemp, blackcurrant, corn gromwell, and Echium plantagineum, and the cyanobacterium Spirulina. SDA can also be synthesized in a lab. A GMO soybean source is approved by the European Food Safety Authority.

References

References

  1. (2012). "Mechanisms of Action of (N-3) Fatty Acids". The Journal of Nutrition.
  2. (2018). "Biofortified Crops Generated by Breeding, Agronomy, and Transgenic Approaches Are Improving Lives of Millions of People around the World". Frontiers in Nutrition.
  3. (2016-05-20). "Variability in Seed Traits in a Collection of Cannabis sativa L. Genotypes". Frontiers in Plant Science.
  4. PubChem. "Stearidonic acid".
  5. "Corn Gromwell". NIAB.
  6. (2014-05-16). "Scientific Opinion on genetically modified soybean MON 87769".
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