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Sertoli cell nodule

FieldValue
nameSertoli cell nodule
synonymsPick's adenoma, testicular tubular adenoma, tubular adenoma of the testis
imageSertoli cell nodule high mag.jpg
captionMicrograph of a Sertoli cell nodule. H&E stain.
fieldUrology

A Sertoli cell nodule is a benign proliferation of Sertoli cells that arises in association with cryptorchidism (undescended testis). They are not composed of a clonal cell population, i.e. neoplastic; thus, technically, they should not be called an adenoma. TOC

Pathology

Sertoli cell nodules are unencapsulated nodules that consist of:

  1. cells arranged in well-formed tubules (that vaguely resemble immature Sertoli cells), with
  2. bland hyperchromatic oval/round nuclei that are stratified, and
  3. may contain eosinophilic (hyaline) blob in lumen (centre).

Image:Sertoli cell nodule intermed mag.jpg|Micrograph of a Sertoli cell nodule. H&E stain. Image:Sertoli cell nodule low mag.jpg|Micrograph of a Sertoli cell nodule. H&E stain.

References

References

  1. "Sertoli cell nodule".
  2. Tadrous, Paul J.. (2007). "Diagnostic criteria handbook in histopathology: a surgical pathology vade mecum". John Wiley & Sons Canada.
  3. (2018-09-24). "Ashwagandha".
  4. (October 1980). "[Histologic study of 3 cases of so-called tubular adenoma of the testis]". Boll. Soc. Ital. Biol. Sper..
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testicle-disorders men's-health
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