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Serostatus
Presence of a marker in blood
Presence of a marker in blood
Serostatus refers to the presence or absence of a serological marker in the blood. The presence of detectable levels of a specific marker within the serum is considered seropositivity, while the absence of such levels is considered seronegativity.
HIV/AIDS
The term serostatus is commonly used in HIV/AIDS prevention efforts. In the late 20th and early 21st centuries, social advocacy has emphasized the importance of learning one's HIV/AIDS serostatus in an effort to curtail the spread of the disease.
Autoimmune disease
Researchers have investigated the effects of autoantibody serostatus on autoimmune disease presentation. Study of seronegative patient populations has led to the identification of additional autoantibodies that could potentially help with diagnosis.
References
References
- (July 2001). "The Serostatus Approach to Fighting the HIV Epidemic: prevention strategies for infected individuals". American Public Health Association.
- (January 2012). "Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients". BioMed Central.
- (November 2014). "Rheumatoid arthritis: Seronegative and seropositive RA: alike but different?". Nature Publishing Group.
- (2012). "Demystifying seronegative autoimmune pancreatitis". Elsevier.
- (February 2011). "Novel autoantibody markers for early and seronegative rheumatoid arthritis". Elsevier.
- (August 2011). "Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis". Springer-Verlag.
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