Surf Wiki
Save to docs
general/secosteroids

From Surf Wiki (app.surf) — the open knowledge base

Secosteroid

Class of chemicals derived from steroids

Class of chemicals derived from steroids

]]

The parent steroid skeleton. The B-ring of the parent steroid is broken between C9 and C10 to yield D vitamins.

A secosteroid () is a type of steroid with a "broken" ring. The word *secosteroid *derives from the Latin verb secare meaning "to cut", and 'steroid'. Secosteroids are described as a subclass of steroids under the IUPAC nomenclature. Some sources instead describe them as compounds derived from steroids.

Types or subclasses of secosteroids are defined by the carbon atoms of the parent steroid skeleton where the ring cleavage has taken place. For example, 9,10-secosteroids are derived from cleavage of the bond between carbon atoms C9 and C10 of the steroid B-ring (similarly 5,6-secosteroids, 13,14-secosteroids, etc.).

The prototypical secosteroid is cholecalciferol (vitamin D3). Its IUPAC systematic is "(5Z,7E)-(3S)-9,10-secocholestra-5,7,10(19)-trien-3-ol".

Some nonsteroidal estrogens, like doisynolic acid (cleaved on the D ring) and allenolic acid, are also secosteroids or secosteroid-like compounds.

References

References

  1. Ayers D. (1972). "Bioscientific Terminology". University of Arizona Press.
  2. (1991). "Dictionary of Steroids". Chapman & Hall.
  3. "Definition of secosteroid". TheFreeDictionary.com.
  4. Hanson JR. (2010). "Steroids: partial synthesis in medicinal chemistry". Nat Prod Rep.
  5. (October 1988). "Doisynolic-type acids--uterotropically potent estrogens which compete poorly with estradiol for cytosolic estradiol receptors.". Journal of Steroid Biochemistry.
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

secosteroids
Want to explore this topic further?

Ask Mako anything about Secosteroid — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report