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Secobarbital/brallobarbital/hydroxyzine

Combination drug


Combination drug

FieldValue
typecombo
component1Brallobarbital
class1Barbiturate
component2Secobarbital
class2Barbiturate
component3Hydroxyzine
class3Antihistamine
imageVesparax.jpg
tradenameVesparax
pregnancy_AU
pregnancy_US
legal_AU
legal_CA
legal_UK
legal_US
legal_UN
legal_NZ
routes_of_administration
CAS_number61112-40-1
ATC_prefix

| Drugs.com =

Secobarbital/brallobarbital/hydroxyzine was a combination tablet containing 50 mg brallobarbital, 150 mg secobarbital and 50 mg hydroxyzine that was used as a sedative. It was sold under the brand name Vesparax. This drug has been withdrawn from the market in most countries.

Hydroxyzine and secobarbital lengthen the half-life of brallobarbital. Because of this long half-life, it has symptoms resembling a hangover on the next day.

Jimi Hendrix was under the influence of Vesparax when he died of asphyxia due to aspiration of vomit on 18 September 1970.

References

References

  1. (March 1964). "[Clinical Application of a New Very Active Hypnotic Associating Sodium Secobarbital, Calcium Brallobarbital and Hydroxyzine (Uc-8130)]". Gazette Médicale de France.
  2. (June 1976). "Peculiar pharmacokinetics of brallobarbital as a source of complications in Vesparax intoxication". Xenobiotica; the Fate of Foreign Compounds in Biological Systems.
  3. (1983). "Efficacy and safety of midazolam and vesparax in treatment of sleep disorders". British Journal of Clinical Pharmacology.
  4. Brown, Tony. (1997). "Jimi Hendrix: The Final Days". Omnibus Press.
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