Reticular connective tissue

Location

Reticular connective tissue is found around the kidney, liver, the spleen, and lymph nodes, Peyer's patches as well as in bone marrow.

Function

The fibers form a soft skeleton (stroma) to support the lymphoid organs (lymph node stromal cells, red bone marrow, and spleen).

Adipose tissue is held together by reticular fibers.

Staining

They can be identified in histology by staining with a heavy metal like silver or the PAS stain that stains carbohydrates. Gordon and Gold can also be used.

Appearance

Reticular connective tissue resembles areolar connective tissue, but the only fibers in its matrix are reticular fibers, which form a delicate network along which fibroblasts called reticular cells lie scattered. Although reticular fibers are widely distributed in the body, reticular tissue is limited to certain sites. It forms a labyrinth-like stroma (literally, "bed or "mattress"), or internal framework, that can support many free blood cells (largely lymphocytes) in lymph nodes, the spleen, and red bone marrow.

Classification

There are more than 20 types of reticular fibers. In Reticular Connective Tissue type III collagen/reticular fiber (100-150 nm in diameter) is the major fiber component. It forms the architectural framework of liver, adipose tissue, bone marrow, spleen and basement membrane, to name a few.

References

Notes

References

1. {{DorlandsDict. eight/000109110. reticular tissue
2. (2007). "Cell biology and histology". Lippincott Williams & Wilkins.
3. "Blue Histology - Connective Tissues".
4. Martini, Frederic H. Fundamentals of Anatomy and Physiology. Seventh Edition. Pearson Benjamin Cummings. United States. 2006.