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Reflux suppressant

A reflux suppressant is any one of a number of drugs used to combat oesophageal reflux. Commonly, following ingestion a 'raft' of alginic acid is created, floating on the stomach contents by carbon dioxide released by the drug. This forms a mechanical barrier to further reflux. Some preparations also contain antacids to protect the oesophagus. Alginate-based reflux suppressants relieve heartburn or regurgitation symptoms in about 60–70% of patients.

Reflux can also be coincidentally reduced by the motility stimulants and antidopaminergics.

References

(2007). "The suppression of gastro-oesophageal reflux by alginates". International Journal of Clinical Practice.
(2010). "Effects, Diagnosis and Management of Extra-Esophageal Reflux".
(2005). "The effect of omeprazole pre-treatment on rafts formed by reflux suppressant tablets containing alginate". Journal of International Medical Research.
"Reflux Suppressants: Mechanisms, Efficacy, and Clinical Use". Claisen, Inc.

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