Rectal bleeding

Signs and symptoms

Those with rectal bleeding may notice bright red blood in their stool. Symptoms associated with rectal bleeding include having several bowel movements in a day, feelings of incomplete rectal evacuation, straining, hard or lumpy stools, feelings of urgency, loose or watery stools, and leakage of bowel movement.

Causes

Bleeding from the rectal area could indicate premalignant polyps or colorectal cancer. Compared to colorectal cancer, anal lesions or benign colorectal conditions are far more common causes of rectal bleeding. Other causes of rectal bleeding include hemorrhoids, full-thickness rectal prolapse, fissures, sentinel tags, ulcers, rhagades, external thromboses with extravasation of blood clot, prolapsed polyps or tags, anal trauma or anal-receptive intercourse, abscess, fistula opening, dermatologic conditions of the perianal region, hypertrophied papilla, and distal proctitis. An ulcer could be caused by Crohn's disease, anal cancer, HIV, or another STD. Inflammatory bowel diseases may also cause rectal bleeding.

Risk factors

Certain medications, such as calcium channel blockers or proton pump inhibitors, can exacerbate anorectal symptoms by causing diarrhea or constipation, or they can exacerbate bleeding (e.g., Coumadin, nonsteroidal anti-inflammatory drugs). A history of hemorrhoidectomy, fissure surgery, fistula surgery, polypectomy, or colectomy may be relevant. Gastrointestinal symptoms can also result from other procedures like gastric bypass or cholecystectomy. Any prior assessment, such as a colonoscopy or flexible sigmoidoscopy, may also be important, as well as any history of polypectomy carried out in connection with one of these operations.

Diagnosis

Any complaint of bleeding should be followed up with a complete blood count (CBC) in order to determine the extent of the bleeding and guide treatment. The partial thromboplastin time (PTT) and the international normalized ratio (INR), which can be used to detect bleeding tendencies, are additional crucial lab tests to obtain.

Testing for STIs, such as gonorrhea and chlamydia, should be conducted on patients who engage in anal receptive sex. No matter if there are other clinical symptoms present or not, endoscopies are the gold standard for examining rectal bleeding and should be completed on patients over 40. To check for a distal source of bleeding, such as internal hemorrhoids, proctitis, rectal ulcers, malignancies, or varices, one can use an anoscope or rigid procto-sigmoidoscope. When proximal lower GI pathology is suspected, a colonoscopy needs to be performed.

If there is a significant amount of bleeding or the patient is too unstable to be put under anesthesia for an endoscopic procedure, CT angiography may be pursued. It could be challenging to pinpoint the precise location of the blood if there is a lot of blood in the stomach.

Tagged red blood cell scintigraphies are a precise way to locate the bleeding vessels and pinpoint the area where they are bleeding. It can be applied to chronic and recurrent rectal bleeding with no apparent cause.

References

References

1. (1997). "Lower gastrointestinal bleeding". Dis. Colon Rectum.
2. (2009). "Rectal bleeding: epidemiology, associated risk factors, and health care seeking behaviour: a population-based study". Colorectal Disease.
3. (1983). "Self-reported dark red bleeding as a marker comparable with occult blood testing in screening for large bowel neoplasms". Br J Surg.
4. (1990). "Rectal bleeding: Patient delay in presentation". Diseases of the Colon & Rectum.
5. Ferguson, Martha A. (2005). "Office Evaluation of Rectal Bleeding". Clinics in Colon and Rectal Surgery.
6. (July 31, 2023). "Rectal Bleeding". StatPearls Publishing.
7. (1996). "Incidence and causes of rectal bleeding in general practice as detected by colonoscopy.". Royal College of General Practitioners.