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Reactive gastropathy


FieldValue
nameReactive gastropathy
imageReactive_gastropathy_-_intermed_mag.jpg
width250
captionMicrograph of a reactive gastropathy. H&E stain.
fieldPathology, gastroenterology

Reactive gastropathy, chemical gastropathy also called gastritis of « C type » or "chemical gastritis" is an abnormality in the stomach caused by chemicals, e.g. bile, alcohol, and characteristically has minimal inflammation.

Cause

Reactive gastropathy has a large number of causes, including:

  • Alcohol use disorder.
  • Bile reflux, such as may be seen post-Billroth II.
  • NSAIDs.

Diagnosis

The diagnosis is by examination of tissue, e.g. a stomach biopsy.

Image: Reactive gastropathy - low mag.jpg | Low mag. Image: Reactive gastropathy - high mag.jpg | High mag.

Relation to gastritis

Reactive gastropathy is morphologically distinct entity that can be separated from gastritis, which by definition has a significant inflammatory component.

As a reactive gastropathy may mimic a (true) gastritis symptomatically and visually in an endoscopic examination, it may incorrectly be referred to as a gastritis. Even aware of the underlying etiology of the pathologic process, e.g. NSAID use, the label "chemical gastritis" is applied to a chemical gastropathy.

References

References

  1. (1988). "Chronic gastritis—a pathogenesis approach". The Journal of Pathology.
  2. (Nov 2005). "Differential diagnosis of reactive gastropathy". Seminars in Diagnostic Pathology.
  3. (Nov 2002). "Chemical gastropathy: a distinct histopathologic entity in children". Journal of Pediatric Gastroenterology and Nutrition.
  4. (May 1986). "Reflux gastritis: distinct histopathological entity?". Journal of Clinical Pathology.
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This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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