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Reactive gastropathy
| Field | Value |
|---|---|
| name | Reactive gastropathy |
| image | Reactive_gastropathy_-_intermed_mag.jpg |
| width | 250 |
| caption | Micrograph of a reactive gastropathy. H&E stain. |
| field | Pathology, gastroenterology |
Reactive gastropathy, chemical gastropathy also called gastritis of « C type » or "chemical gastritis" is an abnormality in the stomach caused by chemicals, e.g. bile, alcohol, and characteristically has minimal inflammation.
Cause
Reactive gastropathy has a large number of causes, including:
- Alcohol use disorder.
- Bile reflux, such as may be seen post-Billroth II.
- NSAIDs.
Diagnosis
The diagnosis is by examination of tissue, e.g. a stomach biopsy.
Image: Reactive gastropathy - low mag.jpg | Low mag. Image: Reactive gastropathy - high mag.jpg | High mag.
Relation to gastritis
Reactive gastropathy is morphologically distinct entity that can be separated from gastritis, which by definition has a significant inflammatory component.
As a reactive gastropathy may mimic a (true) gastritis symptomatically and visually in an endoscopic examination, it may incorrectly be referred to as a gastritis. Even aware of the underlying etiology of the pathologic process, e.g. NSAID use, the label "chemical gastritis" is applied to a chemical gastropathy.
References
References
- (1988). "Chronic gastritis—a pathogenesis approach". The Journal of Pathology.
- (Nov 2005). "Differential diagnosis of reactive gastropathy". Seminars in Diagnostic Pathology.
- (Nov 2002). "Chemical gastropathy: a distinct histopathologic entity in children". Journal of Pediatric Gastroenterology and Nutrition.
- (May 1986). "Reflux gastritis: distinct histopathological entity?". Journal of Clinical Pathology.
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