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POU2F1
Protein-coding gene in the species Homo sapiens
Protein-coding gene in the species Homo sapiens
POU domain, class 2, transcription factor 1 is a protein that in humans is encoded by the POU2F1 gene.
Interactions
POU2F1 has been shown to interact with:
- EPRS,
- Glucocorticoid receptor,
- Glyceraldehyde 3-phosphate dehydrogenase,
- Host cell factor C1,
- Ku80,
- MNAT1
- NPAT,
- Nuclear receptor co-repressor 2,
- POU2AF1,
- RELA,
- Retinoid X receptor alpha,
- SNAPC4,
- Sp1 transcription factor, and
- TATA binding protein.
References
References
- (October 1991). "Differential phosphorylation of the transcription factor Oct1 during the cell cycle". Science.
- "Entrez Gene: POU2F1 POU domain, class 2, transcription factor 1".
- (March 1998). "Interaction of Oct-1 and automodification domain of poly(ADP-ribose) synthetase". FEBS Lett..
- (September 1999). "Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoter". J. Biol. Chem..
- (October 1999). "Developmental effects of ectopic expression of the glucocorticoid receptor DNA binding domain are alleviated by an amino acid substitution that interferes with homeodomain binding". Mol. Cell. Biol..
- (June 1998). "Recruitment of octamer transcription factors to DNA by glucocorticoid receptor". Mol. Cell. Biol..
- (January 1999). "HCF-dependent nuclear import of VP16". EMBO J..
- (March 1993). "Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus alpha-trans-induction factor (VP16)". J. Biol. Chem..
- (May 2001). "The binding of Ku antigen to homeodomain proteins promotes their phosphorylation by DNA-dependent protein kinase". J. Biol. Chem..
- (October 2002). "Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication". Biochim. Biophys. Acta.
- (November 1997). "The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors". J. Biol. Chem..
- (July 2003). "Gene switching by metabolic enzymes--how did you get on the invitation list?". Cell.
- (March 2001). "Silencing mediator for retinoid and thyroid hormone receptors interacts with octamer transcription factor-1 and acts as a transcriptional repressor". J. Biol. Chem..
- (October 1999). "Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface". Genes Dev..
- (June 2001). "Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator". Biochemistry.
- (May 2002). "Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors". Hum. Mol. Genet..
- (July 1999). "Functional interaction between Oct-1 and retinoid X receptor". J. Biol. Chem..
- (January 1998). "The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1". Mol. Cell. Biol..
- (March 2002). "Crystallization of the Oct-1/SNAP190 peptide/DNA complex". Acta Crystallogr. D.
- (June 1996). "The transcription factors Sp1 and Oct-1 interact physically to regulate human U2 snRNA gene expression". Nucleic Acids Res..
- (July 2000). "A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening". Mol. Cell. Biochem..
- (May 1994). "The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP". Nucleic Acids Res..
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