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Polyprenol reductase

Class of enzymes

Field	Value
Name	Polyprenol reductase
EC_number	1.3.1.94

Polyprenol reductase (, SRD5A3 (gene), DFG10 (gene)) is an enzyme with systematic name **. This enzyme catalyses the following chemical reaction

: ditrans, polycis-dolichol + NADP+ \rightleftharpoons ditrans, polycis-polyprenol + NADPH + H+

The reaction occurs in the reverse direction.

References

(May 1993). "Formation of dolichol from dehydrodolichol is catalyzed by NADPH-dependent reductase localized in microsomes of rat liver". The Journal of Biological Chemistry.
(July 2010). "SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder". Cell.

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ec-1.3.1

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