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Pindobind

Pindobind is a compound developed by researchers associated with Stanford University, identified as a central nervous system depressant, which generated a response in animals reducing offensive actions such as chasing, while also notably reducing tendencies of the test animal to evade when stimulated to do so. It acts as an irreversible beta blocker and irreversible 5-HT1A receptor antagonist.

References

References

  1. Peroutka, Stephen J.. (Jul 20, 1993). "Method for relieving anxiety using 5-hydroxytryptamine-1a-receptor-binding compounds".
  2. (1993). "Effects of pindobind 5-hydroxytryptamine1A (5-HT1A), a novel and potent 5-HT1A antagonist, on social and agonistic behaviour in male albino mice". Pharmacology Biochemistry and Behavior.
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This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

5-ht1a-antagonists beta-blockers indole-ethers-at-the-benzene-ring irreversible-antagonists alkylating-agents acetamides organobromides n-tert-butyl-phenoxypropanolamines
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