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Pediatric end-stage liver disease

Field	Value
name	Pediatric end-stage liver disease
purpose	Severity Scoring System for Children (hepatic)
DiseasesDB
ICD10
MedlinePlus
eMedicine
OPS301
LOINC

Note

PELD redirects here. For the plastic see Low-density polyethylene.

Pediatric end-stage liver disease (PELD) is a disease severity scoring system for children under 12 years of age. It is calculated from the patient's albumin, bilirubin, and international normalized ratio (INR) together with the patient's age and degree of growth failure. This score is also used by the United Network for Organ Sharing (UNOS) for prioritizing allocation of liver transplants.

Determination

PELD uses the patient's values for serum bilirubin, serum albumin, the international normalized ratio for prothrombin time (INR), whether the patient is less than 1 year old, and whether the patient has growth failure (

:PELD = 4.80[Ln serum bilirubin (mg/dL)] + 18.57[Ln INR] - 6.87[Ln albumin (g/dL)] + 4.36(

Usage

The PELD score calculated for any given patient is correlated to their prognosis and how likely they are to die within a certain time period. A higher score correlates with a more critical condition. Thus, liver donations are usually allocated by UNOS according to the PELD score to maximize the life-saving capability of each donated liver.

References

"Pediatric Liver Clinic".
"MELD/PELD Calculator Documentation".
(2018-11-01). "Accuracy of the Pediatric End-stage Liver Disease Score in Estimating Pretransplant Mortality Among Pediatric Liver Transplant Candidates.". JAMA Pediatrics.
"Questions & Answers for Transplant Candidates about MELD and PELD". UNOS.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

diseases-of-liver medical-scoring-system digestive-system-procedures

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