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Oscillation (cell signaling)

Type of cell signaling

Oscillations are an important type of cell signaling characterized by the periodic change of the system in time. Oscillations can take place in a biological system in a multitude of ways. Positive feedback loops, on their own or in combination with negative feedback are a common feature of oscillating biological systems.

Examples

Genetic oscillation

One of the most common forms of biological oscillation is genetic oscillation, which can take place when a transcription factor binds and represses its own promoter. This type of regulatory system is able to successfully describe the NFkB-IkB and p53-Mdm52 biological oscillating systems.

Relaxation oscillations

Relaxation oscillation takes place in the context of a bi-stable system. It is characterized by the periodic switching between two stable states.

References

Kruse & Jülicher. Oscillations in Biology. 2005
Kholodenko. Cell-signaling dynamics in time and space. 2006

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

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