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Non-noradrenergic, non-cholinergic transmitter

Group of signaling molecules in the gut


Group of signaling molecules in the gut

A non-noradrenergic, non-cholinergic transmitter (NANC) is a neurotransmitter of the enteric nervous system (ENS) that is neither acetylcholine, norepinephrine, nor epinephrine.

Comparison table

This table compares different NANCs in the PNS:

NeurotransmitterTypeauthor=Rang, H. P.title=Pharmacologypublisher=Churchill Livingstonelocation=Edinburghyear=2003isbn=0-443-07145-4 }} Page 132Function
ATPnon-peptidepostganglionic sympathetic neurons (e.g. in blood vessels & vas deferens)Fast depolarization/contraction (vasoconstriction)
GABAnon-peptideENSsperistalsis
5-HTnon-peptideENSsperistalsis
dopaminenon-peptidesome SNSs (e.g. kidney)vasodilation
NOnon-peptidegastric nerves & Pelvic Nerve
NPYpeptidepostganglionic sympathetic neurons (e.g. blood vessels)
VIPpeptide
GnRHpeptidesympathetic ganglia
substance Ppeptide
CGRPpeptidenon-myelinated sensory neurons

References

References

  1. Rang, H. P.. (2003). "Pharmacology". Churchill Livingstone.
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