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Non-noradrenergic, non-cholinergic transmitter
Group of signaling molecules in the gut
Group of signaling molecules in the gut
A non-noradrenergic, non-cholinergic transmitter (NANC) is a neurotransmitter of the enteric nervous system (ENS) that is neither acetylcholine, norepinephrine, nor epinephrine.
Comparison table
This table compares different NANCs in the PNS:
| Neurotransmitter | Type | author=Rang, H. P. | title=Pharmacology | publisher=Churchill Livingstone | location=Edinburgh | year=2003 | isbn=0-443-07145-4 }} Page 132 | Function |
|---|---|---|---|---|---|---|---|---|
| ATP | non-peptide | postganglionic sympathetic neurons (e.g. in blood vessels & vas deferens) | Fast depolarization/contraction (vasoconstriction) | |||||
| GABA | non-peptide | ENSs | peristalsis | |||||
| 5-HT | non-peptide | ENSs | peristalsis | |||||
| dopamine | non-peptide | some SNSs (e.g. kidney) | vasodilation | |||||
| NO | non-peptide | gastric nerves & Pelvic Nerve | ||||||
| NPY | peptide | postganglionic sympathetic neurons (e.g. blood vessels) | ||||||
| VIP | peptide | |||||||
| GnRH | peptide | sympathetic ganglia | ||||||
| substance P | peptide | |||||||
| CGRP | peptide | non-myelinated sensory neurons |
References
References
- Rang, H. P.. (2003). "Pharmacology". Churchill Livingstone.
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