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Nasal EPAP

Snoring and sleep apnea treatment device

Field	Value
name	Nasal expiratory positive airway pressure

Nasal expiratory positive airway pressure (Nasal EPAP) is a treatment for obstructive sleep apnea (OSA) and snoring.

Contemporary EPAP devices have two small valves that allow air to be drawn in through each nostril, but not exhaled; the valves are held in place by adhesive tabs on the outside of the nose. The mechanism by which EPAP may work is not clear; it may be that the resistance to nasal exhalation leads to a buildup in CO2 which in turn increases respiratory drive, or that resistance to exhalation generates pressure that forces the upper airway to open wider.

In OSA it appears to be effective to reduce but not eliminate apnea for people with mild to moderate OSA (Apnea–hypopnea index

EPAP is unlikely to be effective in people with significant nasal obstruction. Side effects that emerged during clinical trials included difficulty breathing, difficulty falling or staying asleep, dry mouth, nasal congestion, headache, difficulty putting on or removing the device, and anxiety.

Ventus Medical received FDA 510K clearance for marketing the Provent EPAP device for OSA in 2009. Ventus received 510K clearance for an EPAP device to treat snoring in June 2012. Ventus was acquired by Theravent Inc. in 2013.

References

(September 2015). "A review of EPAP nasal device therapy for obstructive sleep apnea syndrome.". Sleep & Breathing.
(2015). "Nasal Expiratory Positive Airway Pressure Devices (Provent) for OSA: A Systematic Review and Meta-Analysis.". Sleep Disorders.
FDA [https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cfm?id=K090398 ProVent 510K table]
FDA [https://www.accessdata.fda.gov/cdrh_docs/pdf9/K090398.pdf Provent 510(k) Summary] April 3, 2009
FDA [https://web.archive.org/web/20160919043947/http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cfm?id=K120665 InVent 510K table]
FDA [https://www.accessdata.fda.gov/cdrh_docs/pdf12/K120665.pdf InVent 510(k) Summary] June 12, 2012
Staff, Sleep Review. April 19, 2013 [http://www.sleepreviewmag.com/2013/04/ventus-medical-closes-its-doors/ Ventus Medical Closing Its Doors]
Bloomberg [https://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapid=28217159 Ventus profile] Page accessed August 15, 2016

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medical-equipment treatment-of-sleep-disorders

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