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Monocytopenia


FieldValue
nameMonocytopenia
fieldhematology

Monocytopenia is a form of leukopenia associated with a deficiency of monocytes.

It has been proposed as a measure during chemotherapy to predict neutropenia, though some research indicates that it is less effective than lymphopenia.

Causes

The causes of monocytopenia include: acute infections, stress, treatment with glucocorticoids, aplastic anemia, hairy cell leukemia, acute myeloid leukemia, treatment with myelotoxic drugs, intestinal resection, and genetic syndromes, as for example MonoMAC syndrome.

Diagnosis

  • Blood Test (CBC) (Normal range of Monocytes: 1-10%) (Normal range in males: 0.2-0.8 x 10 3 /microliter)

  • Blood test checking for monocytopenia (Abnormal ranges:

Treatment

Monocytopenia may be treated with hematopoietic stem cell transplantation.

References

References

  1. (1999). "Early monocytopenia after chemotherapy as a risk factor for neutropenia". [[Am. J. Clin. Oncol.]].
  2. (2006). "Which one is a risk factor for chemotherapy-induced febrile neutropenia in childhood solid tumors: early lymphopenia or monocytopenia?". [[Pediatr Hematol Oncol]].
  3. (2005). "Harrison's principles of internal medicine.". McGraw-Hill.
  4. "Monocytopenia - Hematology and Oncology".
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