From Surf Wiki (app.surf) — the open knowledge base

MMDA-3b

Field	Value
image	MMDA-3b.svg
image_class	skin-invert-image
routes_of_administration	Oral
class	Serotonergic psychedelic; Hallucinogen; Serotonin releasing agent
ATC_prefix	None
onset	Unknown
duration_of_action	Unknown
CAS_number	23693-20-1
PubChem	44374894
ChemSpiderID	23231727
UNII	FM6SU6FD7Y
ChEMBL	159299
synonyms	4-MeO-2,3-MDA; 4-Methoxy-2,3-methylenedioxyamphetamine; 2,3-Methylenedioxy-4-methoxyamphetamine; 4-Methoxy-ORTHO-MDA; 4-MeO-ORTHO-MDA
IUPAC_name	1-(7-methoxy-1,3-benzodioxol-4-yl)propan-2-amine
C	11	H=15	N=1	O=3
SMILES	CC(CC1=C2C(=C(C=C1)OC)OCO2)N
StdInChI	1S/C11H15NO3/c1-7(12)5-8-3-4-9(13-2)11-10(8)14-6-15-11/h3-4,7H,5-6,12H2,1-2H3
StdInChIKey	CLRZDDLQTLKYFH-UHFFFAOYSA-N

| Drugs.com =

| elimination_half-life =

MMDA-3b, also known as 4-methoxy-2,3-methylenedioxyamphetamine (4-MeO-2,3-MDA), is a psychedelic drug of the phenethylamine, amphetamine, and MDxx families related to ORTHO-MDA (2,3-MDA). It is the 4-methoxy derivative of ORTHO-MDA and is a positional isomer of MMDA (5-MeO-3,4-MDA) and related compounds like MMDA-2 (6-MeO-3,4-MDA) and MMDA-3a (2-MeO-3,4-MDA).

MMDA-3b was included as an entry in Alexander Shulgin's book PiHKAL (Phenethylamines I Have Known and Loved). He lists its dose as greater than 80mg orally and its duration as unknown. Shulgin describes 60mg as being definitely active, qualitatively like 3,4-methylenedioxyamphetamine (MDA), but quantitatively perhaps less, whereas an 80mg dose of MMDA-3b was said to be no more effective than the 60mg dose. He also says that it is similar at these doses to 20mg MMDA-3a and may be about 3-fold less potent than MMDA-3a. Elsewhere, MMDA-3b is described as 3-fold more potent than mescaline. Little is known about the drug. The chemical synthesis of MMDA-3b was also described in PiHKAL.

MMDA-3b has been found to act as an efficacious serotonin releasing agent with little effect on dopamine similarly to MMDA. For comparison, MDA and MDMA release both serotonin and dopamine, whereas MMDA-2 releases neither serotonin nor dopamine.

MMDA-3b was first described in the scientific literature by Shulgin in 1964. It was subsequently described in greater detail by Shulgin in his book PiHKAL in 1991. Other 2,3-MDA positional isomers of MMDA-3b include MMDA-4 and MMDA-5.

MMDA-3b is a controlled substance in Canada under phenethylamine blanket-ban language.

References

Shulgin, Alexander T.. (1978). "Stimulants". Springer US.
{{CitePiHKAL https://erowid.org/library/books_online/pihkal/pihkal135.shtml
(1994). "Hallucinogens: An Update". National Institute on Drug Abuse.
(1975). "Hallucinogenic Agents". Wright-Scientechnica.
(March 1991). "3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine". Pharmacol Biochem Behav.
(July 1964). "Psychotomimetic amphetamines: methoxy 3,4-dialkoxyamphetamines". Experientia.
"Controlled Drugs and Substances Act".

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

methoxyphenethylamines methylenedioxyphenethylamines pihkal psychedelic-phenethylamines serotonin-releasing-agents substituted-amphetamines

Want to explore this topic further?

Ask Mako anything about MMDA-3b — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report