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Mitiglinide

Chemical compound

Chemical compound

| Drugs.com =

Mitiglinide (INN, trade name Glufast) is a drug for the treatment of type 2 diabetes.

Mitiglinide belongs to the meglitinide (glinide) class of blood glucose-lowering drugs and is currently co-marketed in Japan by Kissei and Takeda. The North America rights to mitiglinide are held by Elixir Pharmaceuticals. Mitiglinide has not yet gained FDA approval.

Pharmacology

Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive potassium KATP channels in pancreatic β cells.

Dosage

Mitiglinide is delivered in tablet form.

References

References

  1. "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary names (Rec. INN): List 40". World Health Organization.
  2. (October 2008). "Mitiglinide: a rapid- and short-acting non-sulfonylurea insulinotropic agent for the treatment of type 2 diabetic patients". Expert Opinion on Pharmacotherapy.
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carboxamides isoindoles meglitinides potassium-channel-blockers carboxylic-acids
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