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Meganuclease
- Homing endonuclease
- homologous recombination
- I-CreI
- Protein engineering
- Protein design
- Genome editing with engineered nucleases
- Genome engineering
- Genetic engineering
References
References
- (2006). "Homing endonuclease structure and function". Quarterly Reviews of Biophysics.
- (2003-06-01). "A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells". Nucleic Acids Research.
- (2007-08-03). "Engineered I-CreI derivatives cleaving sequences from the human XPC gene can induce highly efficient gene correction in mammalian cells". Journal of Molecular Biology.
- (2010-07-01). "Meganucleases can restore the reading frame of a mutated dystrophin". Gene Therapy.
- (2002). "Mutations altering the cleavage specificity of a homing endonuclease". Nucleic Acids Research.
- (2004). "Isolation and Characterization of New Homing Endonuclease Specificities at Individual Target Site Positions". Journal of Molecular Biology.
- (2006). "Homing endonuclease I-CreI derivatives with novel DNA target specificities". Nucleic Acids Research.
- (2006). "Engineering of Large Numbers of Highly Specific Homing Endonucleases that Induce Recombination on Novel DNA Targets". Journal of Molecular Biology.
- (2006). "A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences". Nucleic Acids Research.
- (2002). "Design, Activity, and Structure of a Highly Specific Artificial Endonuclease". Molecular Cell.
- (2009). "Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffolds". Nucleic Acids Research.
- (2010). "Heritable targeted mutagenesis in maize using a designed endonuclease". The Plant Journal.
- http://www.research.bayer.com/en/straight-into-the-cotton-genome.aspx{{full citation needed. (January 2013)
- (2014-02-01). "megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering". Nucleic Acids Research.
- (2012-10-01). "Coupling endonucleases with DNA end-processing enzymes to drive gene disruption". Nature Methods.
- (2013-01-01). "High frequency targeted mutagenesis using engineered endonucleases and DNA-end processing enzymes". PLOS ONE.
- (2012-08-31). "5′-Cytosine-Phosphoguanine (CpG) Methylation Impacts the Activity of Natural and Engineered Meganucleases". The Journal of Biological Chemistry.
- (2012-03-29). "Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases". Nucleic Acids Research.
- "US Patent for Chromosomal modification involving the induction of double-stranded DNA cleavage and homologous recombination at the cleavage site Patent (Patent # 8,921,332 issued December 30, 2014) - Justia Patents Search".
- "Cellectis announces the issuance by the USPTO of a patent covering a seminal nuclease-based "gene editing" method {{!}} cellectis".
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