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MDAT

Chemical compound

Field	Value
image	6,7-Methylenedioxy-2-aminotetralin.svg
image_class	skin-invert-image
width	250px
class	Serotonin releasing agent; Entactogen
ATC_prefix	None
legal_status	Uncontrolled
index2_label	hydrochloride
CAS_number_Ref
CAS_number	101625-35-8
CAS_number2_Ref
CAS_number2	3446-21-8
UNII_Ref
UNII	28IR5LC41Q
UNII2_Ref
UNII2	BOX4U52EET
PubChem	36483
ChemSpiderID	33531
synonyms	6,7-MDAT; 6,7-Methylenedioxy-2-aminotetralin
IUPAC_name	5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxol-6-amine
C	11	H=13	N=1	O=2
SMILES	C3Cc1cc2OCOc2cc1CC3N

MDAT, also known as 6,7-methylenedioxy-2-aminotetralin, is a drug of the 2-aminotetralin family developed in the 1990s by a team at Purdue University led by David E. Nichols. It appears to act as a serotonin releasing agent based on rodent drug discrimination assays comparing it to MDMA, in which it fully substitutes for, and additionally lacks any kind of serotonergic neurotoxicity. Hence, MDAT is considered likely to be a non-neurotoxic, putative entactogen in humans.

References

(February 1990). "Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry.

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2-aminotetralins david-e.-nichols designer-drugs entactogens methylenedioxyphenethylamines serotonin-releasing-agents

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