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Malate dehydrogenase (NAD(P)+)

Field	Value
Name	Malate dehydrogenase (NAD(P)+)
EC_number	1.1.1.299

Malate dehydrogenase (NAD(P)+) (, MdH II, NAD(P)+-dependent malate dehyrogenase) is an enzyme with systematic name (S)-malate:NAD(P)+ oxidoreductase. This enzyme catalyses the following chemical reaction:

The enzyme was characterized from the methanogenic archaeon Methanobacterium thermoautotrophicum, catalyses only the reduction of oxaloacetate, and can use NAD+ or NADP+ with similar specific activity. It is different from EC 1.1.1.37 (malate dehydrogenase (NAD+)), EC 1.1.1.82 (malate dehydrogenase (NADP+)) and EC 1.1.5.4 (malate dehydrogenase (quinone)).

References

(July 1998). "Two malate dehydrogenases in Methanobacterium thermoautotrophicum". Archives of Microbiology.
{{KEGG enzyme. 1.1.1.299

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ec-1.1.1

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