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List of conditions treated with hematopoietic stem cell transplantation

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Hematopoietic stem cell transplantation may be used to treat a number of conditions both congenital and acquired.

Acquired

Malignancies
- Hematological
  - Leukemias
    - Acute lymphoblastic leukemia (ALL)
    - Acute myeloid leukemia (AML)
    - Chronic lymphocytic leukemia (CLL)
    - Chronic myelogenous leukemia (CML), accelerated phase or blast crisis
  - Lymphomas
    - Hodgkin's disease
    - Non-Hodgkin's lymphoma
  - Myelomas
    - Multiple myeloma (Kahler's disease)
- Solid tumor cancers
  - Neuroblastoma
  - Desmoplastic small round cell tumor
  - Ewing's sarcoma
  - Choriocarcinoma
Hematologic disease
- Phagocyte disorders
  - Myelodysplasia
- Anemias
  - Paroxysmal nocturnal hemoglobinuria (PNH; severe aplasia)
  - Aplastic anemia
  - Acquired pure red cell aplasia
- Myeloproliferative disorders
  - Polycythemia vera
  - Essential thrombocytosis
  - Myelofibrosis
Metabolic disorders
- Amyloidoses
  - Amyloid light chain (AL) amyloidosis
Environmentally-induced diseases
- Radiation poisoning
Viral diseases
- HTLV
- HIV
Autoimmune diseases
- Multiple sclerosis

Congenital

Lysosomal storage disorders
- Lipidoses (disorders of lipid storage)
  - Neuronal ceroid lipofuscinoses
    - Infantile neuronal ceroid lipofuscinosis (INCL, Santavuori disease,)
    - Jansky–Bielschowsky disease (late infantile neuronal ceroid lipofuscinosis)
  - Sphingolipidoses
    - Niemann–Pick disease
    - Gaucher disease
  - Leukodystrophies
    - Adrenoleukodystrophy
    - Metachromatic leukodystrophy
    - Krabbe disease (globoid cell leukodystrophy)
- Mucopolysaccharidoses
  - Hurler syndrome (MPS I H, α-L-iduronidase deficiency)
  - Scheie syndrome (MPS I S)
  - Hurler–Scheie syndrome (MPS I H-S)
  - Hunter syndrome (MPS II, iduronidase sulfate deficiency)
  - Sanfilippo syndrome (MPS III)
  - Morquio syndrome (MPS IV)
  - Maroteaux–Lamy syndrome (MPS VI)
  - Sly syndrome (MPS VII)
- Glycoproteinoses
  - Mucolipidosis II (I-cell disease)
  - Fucosidosis
  - Aspartylglucosaminuria
  - Alpha-mannosidosis
- Other
  - Wolman disease (acid lipase deficiency)
Immunodeficiencies
- T-cell deficiencies
  - Ataxia-telangiectasia
  - DiGeorge syndrome
- Combined T- and B-cell deficiencies
  - Severe combined immunodeficiency (SCID), all types
- Well-defined syndromes
  - Wiskott–Aldrich syndrome
- Phagocyte disorders
  - Kostmann syndrome
  - Shwachman–Diamond syndrome
- Immune dysregulation diseases
  - Griscelli syndrome, type II
- Innate immune deficiencies
  - NF-Kappa-B Essential Modulator (NEMO) deficiency (Inhibitor of Kappa Light Polypeptide Gene Enhancer in B Cells Gamma Kinase deficiency)
Hematologic diseases
- Hemoglobinopathies
- Sickle cell disease
- β thalassemia major (Cooley's anemia)
- Anemias
  - Aplastic anemia
    - Diamond–Blackfan anemia
    - Fanconi anemia
- Cytopenias
  - Amegakaryocytic thrombocytopenia
- Hemophagocytic syndromes
  - Hemophagocytic lymphohistiocytosis (HLH)

References

(2009). "Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation". [[N Engl J Med]].
"Conditions stem cell transplant can cure".

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