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List of antiviral drugs

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Antiviral drugs are different from antibiotics. Flu antiviral drugs are different from antiviral drugs used to treat other infectious diseases such as COVID-19. Antiviral drugs prescribed to treat COVID-19 are not approved or authorized to treat flu.

Antiviral	Use	Manufacturer	Component	Type	Year approved
Abacavir	HIV	ViiV Healthcare		Nucleoside analogue reverse transcriptase inhibitor (NRTI)	1998
Acyclovir (Aciclovir)	Herpes simplex, chickenpox, varicella zoster virus	GSK		guanosine analogue RTI	1981
Adefovir	vauthors = Marcellin P, Chang TT, Lim SG, Tong MJ, Sievert W, Shiffman ML, Jeffers L, Goodman Z, Wulfsohn MS, Xiong S, Fry J, Brosgart CL	display-authors = 6	title = Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B	journal = The New England Journal of Medicine	volume = 348	issue = 9	pages = 808–16	date = February 2003	pmid = 12606735	doi = 10.1056/NEJMoa020681	url = https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1053&context=intmed_pubs	doi-access = free }}	Gilead Sciences	RTI	2002 (FDA), 2003 (EU)
Amantadine	Influenza			Influenza A virus M2 proton channel antagonist	1966
Ampligen	Avian Influenza			Immunomodulatory double-stranded RNA	2016 (Argentina)
Amprenavir (Agenerase)	HIV			Protease inhibitor (PI)	1999 (FDA)
Atazanavir	HIV			PI	2015 (FDA)
Atripla (Efavirenz/emtricitabine/tenofovir)	HIV				1998
Baloxavir marboxil (Xofluza)	Influenza A/B			Cap snatching endonuclease inhibitor	2018
Biktarvy (Bictegravir/emtricitabine/tenofovir alafenamide)	HIV	Gilead Sciences			2018
Boceprevir	Hepatitis C genotype 1	Schering-Plough, then Merck Group		Protease inhibitor
Bulevirtide	Hepatitis D/B			Sodium/bile acid cotransporter inactivator	2020 (EU)
Cidofovir	AIDS			Viral DNA Polymerase inhibitor	1996 (FDA)
Cobicistat (Tybost)	HIV			human CYP3A protein inhibitor
Combivir (Lamivudine/Zidovudine)	HIV				1997 (FDA)
Daclatasvir (Daklinza)	Hepatitis C			NS5A inhibitor
Darunavir	HIV		antiretroviral	HIV PI
Delavirdine	HIV		antiretroviral	NNRTI
Descovy (Emtricitabine/tenofovir alafenamide)	Hepatitis B
Didanosine	HIV			Adenosine analogue RTI	1991 (FDA)
Docosanol	Herpes Simplex			Entry inhibitor	2000 (FDA)
Dolutegravir	HIV			Integrase inhibitor
Doravirine (Pifeltro)	HIV	Merck & Co		NNRTI	2018 (FDA)
Edoxudine	Herpes Simplex			Thymidine analogue inhibitor
Efavirenz	HIV	Mylan		NNRTI	1998
Elvitegravir	HIV	Gilead Sciences		Integrase inhibitor
Emtricitabine	HIV	Gilead Sciences		NRTI	2003
Enfuvirtide	HIV			Entry inhibitor	2003
Ensitrelvir	COVID-19	Shionogi		[3C-like](3c-like-protease) protease inhibitor
Entecavir	HIV			NRTI	2005
Etravirine (Intelence)	HIV			NNRTI	2008
Famciclovir	Herpes Zoster			Guanosine analogue	1994
Fomivirsen	AIDS		Anti-sense oligonucleotide	Anti-sense
Fosamprenavir	HIV	ViiV Healthcare		Amprenavir pro-drug	2003 (FDA), 2004 (EMA)
Foscarnet	Herpes			Pyrophosphate analogue DNA polymerase inhibitor	1991
Ganciclovir (Cytovene)	0-9757919-2-3}}			Competitive nucleoside analogue dGTP inhibitor	1988
Ibacitabine	Herpes labialis
Ibalizumab (Trogarzo)	HIV			Entry inhibitor	2018
Idoxuridine	Herpes			dU analogue inhibitor	1962
Imiquimod	Genital wart, Basal cell carcinoma, Actinic keratosis			Opioid growth factor receptor (OGFr) agonist	1997
Inosine pranobex	Herpes Simplex			Thymus hormone immunostimulant
Indinavir	HIV			PI	1996
Lamivudine	HIV			cytidine analogue RTI
Letermovir (Prevymis)	Cytomegalovirus (CMV)
Lopinavir	HIV
Loviride	HIV
Maraviroc	HIV			entry inhibitor
Methisazone	Smallpox
Molnupiravir	COVID-19	Merck & Co.		viral RNA polymerase inhibitor
Moroxydine	Influenza
Nelfinavir	HIV
Nirmatrelvir/ritonavir (Paxlovid)	COVID-19	Pfizer		[3C-like protease](3c-like-protease) inhibitor (Nirmatrelvir) / inhibition of metabolism of nirmatrelvir (ritonavir)
Nevirapine	HIV			non-nucleoside reverse transcriptase inhibitor
Nitazoxanide	Broad-spectrum antiviral		thiazolide
Norvir	HIV
Oseltamivir (Tamiflu)	Influenza			neuraminidase inhibitor
Peramivir (Rapivab)	Influenza
Penciclovir	Herpes
Pleconaril	Picornavirus	Schering-Plough
Podophyllotoxin	Genital wart
Raltegravir	HIV			Integrase inhibitor
Raphamin
Remdesivir	COVID-19			viral RNA polymerase inhibitor
Ribavirin	Hepatitis C			nucleoside analogue reverse transcriptase inhibitor
Rilpivirine (Edurant)	HIV
Rimantadine	Influenza A			M2 proton channel antagonist
Ritonavir	HIV			HIV-1 protease inhibitor
Saquinavir	HIV
Simeprevir (Olysio)	Hepatitis C
Sofosbuvir	vauthors = Berden FA, Kievit W, Baak LC, Bakker CM, Beuers U, Boucher CA, Brouwer JT, Burger DM, van Erpecum KJ, van Hoek B, Hoepelman AI, Honkoop P, Kerbert-Dreteler MJ, de Knegt RJ, Koek GH, van Nieuwkerk CM, van Soest H, Tan AC, Vrolijk JM, Drenth JP	title = Dutch guidance for the treatment of chronic hepatitis C virus infection in a new therapeutic era	journal = The Netherlands Journal of Medicine	volume = 72	issue = 8	pages = 388–400	date = October 2014	pmid = 25387551 }}			nucleoside analogue reverse transcriptase inhibitor
Stavudine	HIV
Taribavirin (Viramidine)	Hepatitis Syndromes in which Ribavirin is active
Telaprevir	Hepatitis C
Telbivudine (Tyzeka)	Hepatitis B
Tenofovir alafenamide	Hepatitis B
Tenofovir disoproxil	Hepatitis B, HIV
Tipranavir	HIV
Trifluridine	Eyes related Herpes
Trizivir	HIV
Tromantadine	Herpes Simplex
Truvada	HIV
Umifenovir (Arbidol)	Influenza			Hemagglutinin inhibitor
Valaciclovir (Valtrex)	Herpes Simplex/Zoster
Valganciclovir (Valcyte)	Cytomegalovirus (CMV)
Vicriviroc	HIV-1	Schering-Plough		pyrimidine CCR5 entry inhibitor
Vidarabine	Herpes Simplex, Varicella Zoster
Zalcitabine	HIV
Zanamivir (Relenza)	Influenza A, Influenza B
Zidovudine	HIV		Antiretroviral

References

(15 December 2022). "What You Should Know about Flu Antiviral Drugs".
"Acyclovir". The American Society of Health-System Pharmacists.
(February 2003). "Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B". The New England Journal of Medicine.
(28 October 2019). "Xofluza- baloxavir marboxil tablet, film coated".
(2008). "Update on viral hepatitis: 2007". Curr. Opin. Gastroenterol..
(27 August 2020). "Tybost- cobicistat tablet, film coated".
(10 October 2019). "Pifeltro- doravirine tablet, film coated".
(9 June 2020). "Intelence- etravirine tablet".
(19 June 2020). "Cytovene IV- ganciclovir sodium injection, powder, lyophilized, for solution".
Rossi S, editor. [[Australian Medicines Handbook]] 2006. Adelaide: Australian Medicines Handbook; 2006. {{ISBN. 0-9757919-2-3
(8 April 2020). "Trogarzo- ibalizumab injection, solution".
(23 March 2020). "Prevymis- letermovir tablet, film coated PREVYMIS- letermovir injection, solution".
"Tamiflu- oseltamivir phosphate capsule TAMIFLU- oseltamivir phosphate powder, for suspension".
(3 August 2020). "Rapivab- peramivir solution".
"Rebetol, Ribasphere (ribavirin) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 28 February 2014. Retrieved 23 February 2014.
(8 June 2020). "Edurant- rilpivirine hydrochloride tablet, film coated".
(October 2014). "Dutch guidance for the treatment of chronic hepatitis C virus infection in a new therapeutic era". The Netherlands Journal of Medicine.
(2006). "Treating HCV with ribavirin analogues and ribavirin-like molecules". The Journal of Antimicrobial Chemotherapy.
"Tenofovir Disoproxil Fumarate". The American Society of Health-System Pharmacists. Archived from the original on 30 November 2016. Retrieved 29 November 2016.
(10 December 2019). "Valtrex- valacyclovir hydrochloride tablet, film coated".
(9 August 2018). "Valcyte- valganciclovir tablet, film coated VALCYTE- valganciclovir hydrochloride powder, for solution".
(21 June 2018). "Relenza- zanamivir powder".
"Zidovudine". NCBI.

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