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Linoleate 10R-lipoxygenase


FieldValue
NameLinoleate 10R-lipoxygenase
EC_number1.13.11.62

Linoleate 10R-lipoxygenase (, 10R-DOX, (10R)-dioxygenase, 10R-dioxygenase) is an enzyme with systematic name linoleate:oxygen (10R)-oxidoreductase. This enzyme catalyses the following chemical reaction

: linoleate + O2 \rightleftharpoons (8E,10R,12Z)-10-hydroperoxy-8,12-octadecadienoate

Linoleate 10R-lipoxygenase is involved in biosynthesis of oxylipins.

References

References

  1. (May 2009). "Leucine/valine residues direct oxygenation of linoleic acid by (10R)- and (8R)-dioxygenases: expression and site-directed mutagenesis oF (10R)-dioxygenase with epoxyalcohol synthase activity". The Journal of Biological Chemistry.
  2. (April 2010). "Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.
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