From Surf Wiki (app.surf) — the open knowledge base

Hydrazine (antidepressant)

Group of antidepressants

Note

a series of antidepressants

The hydrazine antidepressants are a group of non-selective, irreversible monoamine oxidase inhibitors (MAOIs) which were discovered and initially marketed in the 1950s and 1960s. Most have been withdrawn due to toxicity, namely hepatotoxicity, but a few still remain in clinical use.

Tranylcypromine, a structurally unrelated MAOI introduced around the same time as the hydrazines, was originally advertised as non-hydrazine as a result of its diminished propensity for causing hepatotoxicity.

List of hydrazine antidepressants

Marketed

Benmoxin (Neuralex, Nerusil) ‡
Iproclozide (Sursum) ‡
Iproniazid (Marsilid) ‡
Isocarboxazid (Marplan)
Mebanazine (Actomol) ‡
Nialamide (Niamid) ‡
Octamoxin (Ximaol, Nimaol) ‡
Phenelzine (Nardil)
Pheniprazine (Catron) ‡
Phenoxypropazine (Drazine) ‡
Pivhydrazine (Tersavid) ‡
Safrazine (Safra) ‡

Legend: ‡ = Withdrawn from the market; † = Partially discontinued; Bolded names indicate major drugs.

Never marketed

Carbenzide
Cimemoxin
Domoxin
Metfendrazine

[[Parkinson's]]

Carbidopa

Tranquillosedative

Centazolone

References

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

hepatotoxins hydrazines monoamine-oxidase-inhibitors

Want to explore this topic further?

Ask Mako anything about Hydrazine (antidepressant) — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report