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Hepatoprotection
Ability of a chemical substance to prevent liver damage
Ability of a chemical substance to prevent liver damage
Hepatoprotection or antihepatotoxicity is the ability of a chemical substance to prevent damage to the liver. This is opposite to hepatotoxicity.
Hepatoprotective molecules used in emergency medicine
- Acetylcysteine is considered the hepatoprotective drug of choice when treating an overdose of acetaminophen/paracetamol.
- Silymarin is given intravenously to treat poisoning from Amanita mushrooms according to the Santa Cruz protocol devised by Dr Todd Mitchell at UCSC.
Herbs with potentially hepatoprotective constituents
-
Astragalus membranaceus
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Brassica
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Silybum marianum, from which silymarin is derived
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Andrographis paniculata
References
References
- "Archived copy".
- (Jan 2011). "Biological analysis of herbal medicines used for the treatment of liver diseases.". Biomedical Chromatography.
- (Sep 1, 2001). "Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.". Mutation Research.
- Andrographis paniculata http://www.stuartxchange.com/Sinta.html
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