Granuloma gluteale infantum

Signs and symptoms

In cases of primary irritant contact dermatitis, the lesions manifest clinically as numerous asymptomatic erythematous papules and nodules in the diaper area.

Causes

Granuloma gluteale infantum is an uncommon dermatosis of infancy with an unknown etiology. Contributing factors include prolonged use of fluorinated steroids, and benzocaine, diaper occlusion in incontinent adults and infants, candidiasis, and irritant contact dermatitis.

Diagnosis

The histological picture shows an underlying hyperplastic epidermis and parakeratosis, accompanied by a non-specific perivascular dermal infiltrate made up of neutrophils, histiocytes, lymphocytes, plasma cells, and eosinophils.

Treatment

In order to treat granuloma gluteale infantum, the diaper area needs to be kept dry and clean, and the irritant should be eliminated or lessened. It is recommended to use a barrier cream, such as zinc oxide.

References

References

1. Rapini, Ronald P.. (2007). "Dermatology: 2-Volume Set". Mosby.
2. (2000). "Granuloma gluteale infantum: a case report". Pediatr Dermatol.
3. (June 7, 2021). "Successful Treatment of Recalcitrant Granuloma Gluteale Infantum with Topical Tacrolimus 0.03% Ointment". Hindawi Limited.
4. (1996). "Granuloma gluteale infantum". Wiley.
5. (1976). "[Granuloma gluteale infantum]". Medicina Cutanea Ibero-latino-americana.
6. (June 1, 2002). "Granuloma Gluteale Adultorum Associated with Use of Topical Benzocaine Preparations: Case Report and Literature Review". SAGE Publications.
7. (1992). "Diaper Area Granuloma of Incontinence". Wiley.
8. (2000). "Granuloma Gluteale Infantum: A Case Report". Wiley.
9. (June 1, 1988). "Granuloma gluteale infantum: an unusual complication of napkin dermatitis.". BMJ.
10. (2010). "A forgotten complication of diaper dermatitis: Granuloma gluteale infantum". Medknow.
11. (August 23, 2018). "Recurrent Granuloma Gluteale Infantum Secondary to Fecal Overflow Incontinence". S. Karger AG.