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Gemeprost

Chemical compound

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Gemeprost (16, 16-dimethyl-trans-delta2 PGE1 methyl ester) is an analogue of prostaglandin E1.

Clinical use

It is used as a treatment for obstetric bleeding.

It is used with mifepristone to terminate pregnancy up to 24 weeks gestation.

Side effects

Vaginal bleeding, cramps, nausea, vomiting, loose stools or diarrhea, headache, muscle weakness; dizziness; flushing; chills; backache; dyspnoea; chest pain; palpitations and mild pyrexia. Rare: Uterine rupture, severe hypotension, coronary spasms with subsequent myocardial infarctions.

References

(August 2025). "Cervagem 1 mg Pessary - Summary of Product Characteristics (SmPC)".
(October 2001). "Double-blind randomized trial of mifepristone in combination with vaginal gemeprost or misoprostol for induction of abortion up to 63 days gestation". Human Reproduction.
Aronson, J. K.. (2015). "Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions". Elsevier Science.

Info: Wikipedia Source

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abortifacients prostaglandins sanofi uterotonics medication-abortion methyl-esters

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