From Surf Wiki (app.surf) — the open knowledge base
Fusaric acid
Fusarinic acid pKa2=? pKa3=?--
Fusaric acid is a picolinic acid derivative and an antibiotic (wilting agent) first isolated from the fungus Fusarium heterosporium.
It is typically isolated from various Fusarium species, and has been proposed for a various therapeutic applications. However, it is primarily used as a research tool.
Its mechanism of action is not well understood. It likely inhibits dopamine beta-hydroxylase (the enzyme that converts dopamine to norepinephrine). It may also have other actions, such as the inhibition of cell proliferation and DNA synthesis. Fusaric acid and analogues also reported as quorum sensing inhibitors.
It is used to make bupicomide.
References
References
- Yabuta et al., J. Agric. Chem. Soc. Jpn. 10, 1059 (1934).
- Tung et al., Eur. J. Med. Chem. https://dx.doi.org/10.1016/j.ejmech.2016.11.044.
This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.
Ask Mako anything about Fusaric acid — get instant answers, deeper analysis, and related topics.
Research with MakoFree with your Surf account
Create a free account to save articles, ask Mako questions, and organize your research.
Sign up freeThis content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.
Report