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Fenadiazole

Chemical compound

Chemical compound

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Fenadiazole (), also known as phénadiazole () and sold under the brand names Hypnazol, Eudormil, and Viodor, is a hypnotic and sedative medication which has been used to treat insomnia but is no longer marketed. It is described as a non-barbiturate hypnotic with marked or profound hypnotic and sedative properties in animals, variable hypnotic effects in humans (rapidly inducing sleep for 6 to 8hours), additional anticonvulsant, antithermal, and spasmolytic effects, and a generally well-tolerated profile in humans (at an average dosage of 200mg/day). The drug was synthesized, pharmacologically characterized, patented, and marketed by the French pharmaceutical company Laboratoires Jacques Logeais between 1960 and 1962. As a hypnotic and sedative, fenadiazole has a unique oxadiazole-based chemical structure. It may be chemically related to certain other hypnotics and sedatives with atypical chemical structures. Fenadiazole was encountered online as a novel designer drug in 2025.

References

References

  1. (1949). "Nordisk veterinärmedicin". Nordisk veterinærmedicin.
  2. (14 November 2014). "The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies". Springer.
  3. (1996). "The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals". Merck Research Laboratories.
  4. (1978). "Organic-chemical Drugs and Their Synonyms: An International Survey, Volume 1". Akademie-Verlag.
  5. (1961). "Unknown". Journal de médecine de Bordeaux et de la région du sud-ouest.
  6. Society of Chemical Industry (Great Britain). (1960). "Reports on the Progress of Applied Chemistry". Society of Chemical Industry.
  7. (1963). "Les hypnotiques". Presses universitaires de France.
  8. "Hypnotic and sedative drug, 2-(o-hydroxyphenyl)-1,3,4-oxadiazole.".
  9. "Derivatives of 1,3,4-oxadiazole".
  10. (1960). "A new nonbarbiturate hypnotic, 2-(o-hydroxyphenyl)-1,3,4-oxadiazole.". Revue Médicale de Nancy.
  11. (31 December 1997). "Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists". Walter de Gruyter.
  12. "Фенадиазол (Fenadiazol)".
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designer-drugs drugs-with-unknown-mechanisms-of-action 2-hydroxyphenyl-compounds hypnotics oxadiazoles sedatives
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