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Famprofazone

NSAID analgesic medication

NSAID analgesic medication

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Famprofazone (Gewodin, Gewolen) is a nonsteroidal anti-inflammatory agent (NSAID) of the pyrazolone series which is available over-the-counter in some countries such as Taiwan. It has analgesic, anti-inflammatory, and antipyretic effects. Famprofazone has been known to produce methamphetamine as an active metabolite, with 15–20% of an oral dose being converted to it. As a result, famprofazone has occasionally been implicated in causing positives on drug tests for amphetamines.

References

References

  1. Swiss Pharmaceutical Society. (2000). "Index Nominum 2000: International Drug Directory (Book with CD-ROM)". Medpharm Scientific Publishers.
  2. (1999). "Concise dictionary of pharmacological agents: properties and synonyms". Kluwer Academic.
  3. (2010). "Famprofazone use can be misinterpreted as methamphetamine abuse". Journal of Analytical Toxicology.
  4. (March 1992). "Plasma and urinary concentrations of methamphetamine after oral administration of famprofazone to man". Xenobiotica; the Fate of Foreign Compounds in Biological Systems.
  5. (1998). "Identification of new urinary metabolites of famprofazone in humans". Journal of Analytical Toxicology.
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amines designer-prodrugs nonsteroidal-anti-inflammatory-drugs pyrazolones stimulants norepinephrine-dopamine-releasing-agents isopropyl-compounds
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