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Extended-spectrum penicillin

Group of antibiotics that have the widest antibacterial spectrum of all penicillins

Group of antibiotics that have the widest antibacterial spectrum of all penicillins

The extended-spectrum penicillins are a group of antibiotics that have the widest antibacterial spectrum of all penicillins. Some sources identify them with antipseudomonal penicillins, others consider these types to be distinct. This group includes the carboxypenicillins and the ureidopenicillins. Aminopenicillins, in contrast, do not have activity against Pseudomonas species, as their positively charged amino group does not hinder degradation by bacterially produced beta-lactamases.

Products

  • Ureidopenicillins
    • Azlocillin
    • Mezlocillin
    • Piperacillin
  • Carboxypenicillins
    • Ticarcillin (generally in the combination ticarcillin/clavulanic acid)
    • Carbenicillin
  • Mecillinam

References

References

  1. Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p917
  2. (2011). "Elsevier's Integrated Review Pharmacology E-Book". Elsevier Health Sciences.
  3. (2011). "Pharmacology". Lippincott Williams & Wilkins.
  4. Golan, David E.. (15 December 2011). "Principles of Pharmacology". Lippincott Williams & Wilkins.
Info: Wikipedia Source

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