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Ethanolamine-O-sulfate


Ethanolamine-O-sulfate (EOS) is an ester of sulfuric acid and ethanolamine. EOS is a GABA transaminase inhibitor which prevents the metabolism of GABA. It is used as a biochemical tool in studies involving GABA.

EOS is also a diuretic and an anticonvulsant.

References

References

  1. [http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=06720|ALDRICH&N5=SEARCH_CONCAT_PNO|BRAND_KEY&F=SPEC 2-Aminoethyl hydrogen sulfate] at [[Sigma-Aldrich]]
  2. (1983). "Ethanolamine-O-sulfate enhances gamma-aminobutyric acid secretion into hypophysial portal blood and lowers serum prolactin concentrations". Neuroendocrinology.
  3. German Patent DE2345291: Diuretic aminoalkyl sulfates; Somani, Pitambar; Martin, Donald Lyons (1974)
  4. (1976). "Anticonvulsant action of ethanolamine-O-sulfate and di-n-propylacetate and the metabolism of γ-aminobutyric acid (GABA) in mice with audiogenic seizures". [[Biochemical Pharmacology (journal).
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