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Dictyoglomi-1 RNA motif


FieldValue
NameDictyoglomi-1 RNA
imageDictyoglomi-1-RNA.svg
captionConsensus secondary structure of Dictyoglomi-1 RNAs. This figure is adapted from a previous publication.
SymbolDictyoglomi-1
RfamRF01703
RNA_typeGene; sRNA;
Tax_domainBacteria;
SO

The Dictyoglomi-1 RNA motif (also called dct-1) is a conserved RNA structure that was discovered via bioinformatics. Only four instances of the RNA were detected, and all are in the bacterial phylum Dictyoglomota (formerly Dictyoglomi), whose members have not been extensively studied. The RNA might have a cis-regulatory role, but the evidence is ambiguous. Because of the few instances of Dictyoglomi-1 RNAs known, it is also unknown whether the RNA structure might extend further in the 5′ or 3′ direction, or in both directions.

The Dictyoglomi-1 RNA motif conserves four bulged-G modules (also called E-loops) Bulged-G modules are often associated with intermolecular interactions, and multiple examples are found in ribosomal RNAs. However the biological role that the four bulged-G modules play in the context of Dictyoglomi-1 RNAs remains unknown.

References

References

  1. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol.
  2. (December 2009). "Exceptional structured noncoding RNAs revealed by bacterial metagenome analysis". Nature.
  3. Westhof E. (2010). "The amazing world of bacterial structured RNAs". Genome Biol.
  4. Lee, JC. (2003). "Structural studies of ribosomal RNA based on cross-analysis of comparative models and three-dimensional crystal structures". University of Texas.
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