Surf Wiki
Save to docs
general/nucleotides

From Surf Wiki (app.surf) — the open knowledge base

Deoxycytidine monophosphate

Deoxycytidine monophosphate (dCMP), also known as deoxycytidylic acid or deoxycytidylate in its conjugate acid and conjugate base forms, respectively, is a deoxynucleotide and one of the four monomers that make up DNA. In a DNA double helix, it will base pair with deoxyguanosine monophosphate.

Medical use

Deoxycytidine monophosphate is a molecule of interest in treating genetic disorders such as thymidine kinase 2 (TK2) deficiency. In the case of TK2 deficiency, dCMP in conjunction with deoxythymidine monophosphate (dTMP) to bypass the deficiency in the TK2 enzyme. Additionally dCMP is an indicator of several metabolite deficiency pathways such as UMP synthase deficiency or orotic aciduria.

References

References

  1. "Human Metabolome Database: Showing metabocard for dCMP (HMDB0001202)".
  2. Garone, Caterina. (August 2014). "Deoxypyrimidine monophosphate bypass therapy for thymidine kinase 2 deficiency". EMBO Molecular Medicine.
  3. PubChem. "Deoxycytidine 5'-monophosphate".
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

nucleotides
Want to explore this topic further?

Ask Mako anything about Deoxycytidine monophosphate — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report